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"Qlucore is indeed an impressive tool. It is very fast and delivers excellent control of the analysis. I really enjoy it."

Ole Ammerpohl, PhD, Kiel University, Germany

DNA METHYLATION

DNA Methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the best characterized epigenetic mechanism. Research has shown that DNA Methylation is manifested in a number of important biological processes and human diseases including cancer.

Key functionality

With Qlucore Omics Explorer, a number of different analyses can be done. For DNA Methylation data, the following functionality will be of specific interest:

Check data for outliers by visual inspection using sample Principal Component Analysis (PCA) plots.
Perform statistical filtering using ANOVA to enhance results.
Generate a list of genes that classifies data based on a selection of statistical tests: f-test, t-tests or regression.
Present results using, for example, heatmaps or PCA plots.